Ask Your Trusted Philadelphia Dentist about the Worm Drug Discovery

The study showed that the Oxantel interferes with an enzyme needed by the bacteria for biofilm formation in a dose-dependent manner, making its efficacy level noteworthy. Oxantel, known as a drug that inhibits fumarate reductase in some bacteria, was then tested in Porphyromonas gingivalis, which is a vital bacterial component found in periodontitis biofilms. Remarkably, Oxantel was also reported to disrupt polymicrobial biofilms containing Tannerella forsythia, and Treponema denticola, which typically are components of periodontal biofilms.

At the end of the study, the researchers claimed to have found that the Oxantel treatment diminished six P. gingivalis gene products and increased 22 gene products, which make up a necessary composition of a genetic unit that controls availability of heme. As periodontitis has been known to affect 30- 47 percent of the adult population, it is best that you consult with a trusted Philadelphia cosmetic dentist like Thomas DeFinnis, DMD of Wynnewood Dental Arts for more knowledge and consultation about this disease.

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